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Longevity Research

SEMAX

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Semax is a next-generation peptide designed to support sharper focus, clearer thinking, stronger memory, and greater mental resilience. Often described as a “brain-performance” peptide, it works with key pathways involved in learning, concentration, and cognitive recovery—helping you feel more switched on, mentally agile, and ready to perform.

Batch details included Manufactured in Canada
$54 CADCAD · shipping and taxes shown at checkout

SEMAX is supplied as 5 mg of lyophilized powder in a sealed glass vial for laboratory research. Confirm the selected vial and batch details before preparation.

Selected strength5 mg
Purity99.08%
TestingHPLC-UV
BatchPP-LOT-034
+ Show Scientific Details− Hide Scientific Details
CAS number80714-61-0
Compound classSynthetic ACTH-derived heptapeptide
Peptide length7 amino acids
SequenceMEHFPGP
Molecular formulaC37H51N9O10S
Molecular weight813.9 g/mol
Research themesNeurotrophic signalling · Neuroprotection · Cognitive models
Scientific profile

Semax is the synthetic heptapeptide Met-Glu-His-Phe-Pro-Gly-Pro, derived from an ACTH(4-7) fragment with a Pro-Gly-Pro extension.

Product guide

SEMAX Explained

A clear, quick look at what SEMAX is, how it works, and why it is being studied.

What is Semax supposed to help with?

Semax is best known for focus, memory, learning, and mental energy. People look into it when they want their brain to feel sharper without relying on a traditional stimulant.

Research Context

Semax is a synthetic ACTH(4-7)-derived heptapeptide with a Pro-Gly-Pro extension. It has been studied in neurotrophic, neuronal-response and neuroprotection models, with a history of regional human use/research. [1]

What might better mental focus feel like?

Think about sitting down to work and actually staying with the task instead of bouncing between tabs, thoughts, and distractions. That steady mental grip is the everyday appeal.

Does Semax feel like caffeine?

It is discussed differently from caffeine. The goal is not a shaky rush or temporary buzz, but clearer thinking and better mental performance through brain-related signaling.

Research Context

Semax does not have one fully settled mechanism. Reported effects involve neurotrophic signalling, melanocortin-related pathways, gene expression and oxidative-stress responses, with mechanisms varying by model. [1]

Can Semax help with memory?

Memory is a major part of its research story. The interest is in helping the brain take in information, hold onto it, and bring it back when needed.

Research Context

Experimental work has examined neurotrophin expression, oxidative-stress pathways, neuronal survival and learning-related biology. Those mechanisms support cognitive research interest but do not establish broad cognitive enhancement in healthy people. [1]

Is Semax mainly for studying or everyday focus?

Both fit the same idea: getting the brain to stay engaged. People are interested during demanding work, study, problem-solving, or any period when mental stamina matters.

Can Semax help when I feel mentally drained?

That is part of the appeal, especially when the brain feels tired before the day is finished. It is studied around mental resilience rather than simply forcing wakefulness.

How is Semax different from Selank?

Semax leans toward focus, memory, and mental drive. Selank leans toward calm, stress, and mood. Think sharper mind versus quieter mind.

Why do people choose Semax?

It offers a different idea from simply consuming more caffeine: support the systems behind attention and learning instead of chasing another short-lived energy spike.

Research Context

Cell and animal research reports neuroprotective and neurotrophic signals, and there is regional human literature. Much of the human evidence is smaller or less independently replicated than modern large multicentre registration trials, so evidence strength should be described accordingly. [1]

Read the full Semax evidence guideStudy design, primary sources, limitations, and unanswered questions.Open guide
Research-use statement

This product is offered for laboratory research only. It is not for human consumption and is not represented as a medicine, treatment, supplement or substitute for an approved product.

Preparation guide

Calculate. Prepare. Store.

Confirm the selected vial and BAC-water amount, enter the target amount, then follow the preparation and storage steps.

Step 1: Calculate

The selected strength automatically opens with the easy starting rule of 100 mcg = 1 unit.

SEMAX · 5 mg selected

Vial Strength
5mg

Easy rule: 100 mcg = 1 unit · Every 1 unit = 100 mcg

Calculated result
U-100 syringe—Enter the target mcg amount

This calculator converts the values entered. It does not choose an amount.

Step 2: Prepare

This 5 mg vial opens with 0.5 mL of BAC water, creating the easy starting rule of 100 mcg = 1 unit.

If the water amount is changed above, use the updated easy rule shown by the calculator.

Do not shake the vialSlowly add the water down the inside wall of the vial, then gently swirl until fully dissolved.

Step 3: Store

Prepared vialsRefrigerate at 2–8°C

Unprepared vialsKeep cool and dry, away from heat, moisture, and direct sunlight

Shipping & delivery

Picked And Shipped Within 24 Hours.

Every order is prepared and packed in Canada with care, accuracy, and attention to detail. In-stock orders are checked and packed within 24 hours, then shipped with Canada Post. Tracking is sent after the parcel’s first carrier scan.

Bilingual Shipped by Canada Post logo with English to the left and French to the right

Customer Reviews

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Lacey HughesVerified buyer
★★★★★
Puffin Peptides

Nice site and helpful chat bot. I’ll be back again.

Kimmy SonnVerified buyer
★★★★★
Puffin Peptides

I can’t believe it but I’ve lost 30lb. It’s been 3 months and felt compelled to write a review. I know it’s not Puffin I have to thank but their site came up in google and brought me here. Thank youuuuuu! <3

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Product documentation

Batch Details

Uploaded documents5 mg
PDF · 5 mgPP-SEMAX-5-MG-R034.pdfPublished for SEMAX 5 mg
View document
ProductSEMAX
Strength5 mg
Catalogue codePP-SEMAX-5-MG
PresentationLyophilized powder in a sealed glass vial
StorageSee vial label and lot-specific documentation
Intended useLaboratory research only · not for human consumption

Only uploaded documents published for the selected vial strength are shown here.

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