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Longevity Research

SS-31

Recharge from the cellular level. SS-31 is a mitochondria-focused research peptide studied for its potential to support energy production, cellular efficiency, recovery, and resilience—making it especially appealing for those interested in performance, endurance, and healthy aging.

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SS-31 is supplied as 50 mg of lyophilized powder in a sealed glass vial for laboratory research. Confirm the selected vial and batch details before preparation.

Selected strength50 mg
Purity99.98%
TestingHPLC-UV
BatchPP-LOT-036
+ Show Scientific Details− Hide Scientific Details
Primary nameElamipretide
AliasesSS-31 · MTP-131 · Bendavia
CAS number736992-21-5
Compound classMitochondria-targeting synthetic tetrapeptide
Peptide length4 amino-acid residues
Sequence notationD-Arg–2,6-dimethyl-Tyr–Lys–Phe-NH2
Molecular formulaC32H49N9O5
Molecular weight639.8 g/mol
Primary target/themeMitochondrial inner-membrane / cardiolipin biology
Scientific profile

Elamipretide (SS-31) is a synthetic mitochondria-targeting tetrapeptide studied for interactions with cardiolipin-associated inner-mitochondrial-membrane biology.

Product guide

SS-31 Explained

A clear, quick look at what SS-31 is, how it works, and why it is being studied.

What is SS-31 supposed to help with?

SS-31 is best known for mitochondrial health, cellular energy, fatigue, and healthy aging. It is designed to protect the tiny power plants that keep cells running.

Research Context

SS-31, also known as elamipretide, is a mitochondria-targeting tetrapeptide studied for effects on mitochondrial membrane biology and bioenergetics. Human trials have explored disease-specific endpoints; broad claims about energy, fatigue or longevity should not exceed those data. [1]

What are mitochondria in plain English?

They are the batteries and power plants inside your cells. Every demanding tissue—from the heart to muscles and brain—depends on them for usable energy.

Research Context

Mitochondria generate ATP through oxidative phosphorylation and also regulate redox signalling and cell stress. Their inner membrane is central to electron transport and energy conversion. [1]

What could healthier mitochondria mean day to day?

Think of a battery that holds power more reliably instead of draining under every demand. The appeal is steadier cellular energy and greater resilience, not a sudden artificial rush.

Research Context

Improved mitochondrial function is a cellular concept, not a guaranteed subjective sensation. Clinical studies must measure specific outcomes such as exercise capacity, cardiac function or fatigue rather than infer them from mechanism alone. [1]

Does SS-31 feel like a stimulant?

No. A stimulant pushes alertness higher for a while. SS-31 is studied for protecting the machinery that makes energy in the first place.

Research Context

No. Elamipretide research concerns mitochondrial structure/function rather than an acute stimulant pathway. A mitochondria-targeting mechanism should not be equated with a caffeine-like effect. [1]

Why is SS-31 discussed for fatigue?

When mitochondria struggle, cells may have difficulty keeping up with energy demands. Supporting that machinery is why fatigue and exercise tolerance are major parts of the SS-31 conversation.

Research Context

Mitochondrial dysfunction can limit ATP production in high-demand tissues, which creates a plausible rationale for fatigue research. Whether that translates to clinically meaningful fatigue improvement depends on the population and trial. [1]

How does SS-31 protect the cell’s power plants?

It is designed to interact with the inner mitochondrial membrane, where energy production happens. Think of reinforcing a power station’s most important working surface.

Research Context

Elamipretide is designed to localize to the inner mitochondrial membrane and interact with cardiolipin-associated membrane biology, which can influence electron transport and mitochondrial efficiency. [1]

Is SS-31 mainly for energy or longevity?

Both ideas are connected. Protecting how cells make energy today may also help researchers understand how tissues maintain function as they age.

Research Context

Human development has focused on defined mitochondrial and disease-related outcomes, while “longevity” remains a broader extrapolation from mitochondrial biology rather than a demonstrated extension of human lifespan. [1]

How is SS-31 different from NAD+?

NAD+ is a working molecule used throughout cellular energy and repair. SS-31 is a peptide designed to target and protect a specific part of the mitochondria.

Research Context

NAD+ is a ubiquitous redox coenzyme used across cellular metabolism and repair; SS-31 is a peptide designed to target mitochondrial membrane biology. They operate at different levels of the energy system. [1]

Read the full SS-31 evidence guideStudy design, primary sources, limitations, and unanswered questions.Open guide
Research-use statement

This product is offered for laboratory research only. It is not for human consumption and is not represented as a medicine, treatment, supplement or substitute for an approved product.

Preparation guide

Calculate. Prepare. Store.

Confirm the selected vial and BAC-water amount, enter the target amount, then follow the preparation and storage steps.

Step 1: Calculate

The selected strength automatically opens with the easy starting rule of 1 mg = 10 units.

SS-31 · 50 mg selected

Vial Strength
50mg

Easy rule: 1 mg = 10 units · Every 10 units = 1 mg

Calculated result
U-100 syringe20 units2 mg at the current water amount

This calculator converts the values entered. It does not choose an amount.

Step 2: Prepare

This 50 mg vial opens with 5 mL of BAC water, creating the easy starting rule of 1 mg = 10 units.

If the water amount is changed above, use the updated easy rule shown by the calculator.

Do not shake the vialSlowly add the water down the inside wall of the vial, then gently swirl until fully dissolved.

Step 3: Store

Prepared vialsRefrigerate at 2–8°C

Unprepared vialsKeep cool and dry, away from heat, moisture, and direct sunlight

Shipping & delivery

Picked And Shipped Within 24 Hours.

Every order is prepared and packed in Canada with care, accuracy, and attention to detail. In-stock orders are checked and packed within 24 hours, then shipped with Canada Post. Tracking is sent after the parcel’s first carrier scan.

Bilingual Shipped by Canada Post logo with English to the left and French to the right

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Product documentation

Batch Details

Uploaded documents50 mg
PDF · 50 mgPP-SS-31-50-MG-R036.pdfPublished for SS-31 50 mg
View document
ProductSS-31
Strength50 mg
Catalogue codePP-SS-31-50-MG
PresentationLyophilized powder in a sealed glass vial
StorageSee vial label and lot-specific documentation
Intended useLaboratory research only · not for human consumption

Only uploaded documents published for the selected vial strength are shown here.

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