Full vial shown · package appearance may vary by batch24/7 Customer Support
Lab tested for purity & quality
Ships from Canada within 24 hours
At Puffin Peptides, we work with an established Canadian manufacturer and handle packaging and fulfilment here in Canada. Keeping the process close to home gives us better visibility into quality, consistency, packaging, and the batches moving through our catalogue.
That means clearer product information, accessible batch documentation, responsive local support, and a more dependable ordering experience from checkout to delivery.
Our focus is simple: well-made research products, straightforward information, and reliable Canadian service.
Fuel your body where energy begins. NAD+ is a naturally occurring coenzyme that helps cells turn nutrients into energy while supporting DNA repair, brain function, metabolism, and healthy aging. Often associated with cellular vitality, it is used to promote sharper performance, stronger recovery, and sustained energy from within.
NAD+ is supplied as 500 mg of lyophilized powder in a sealed glass vial for laboratory research. Confirm the selected vial and batch details before preparation.
NAD+ is the oxidized form of nicotinamide adenine dinucleotide, a ubiquitous cellular coenzyme involved in redox reactions and used as a substrate by multiple enzyme families.
Protonation and salt forms have slightly different formulae and masses. The displayed identity is tied to the referenced NAD record.
This 500 mg vial opens with 50 mL BAC water.
The default easy rule is 1 mg = 10 units on a U-100 syringe. Changing the water amount updates that relationship automatically.
Want to measure an mg amount?Open the reconstitution calculatorStore unprepared vials in a cool, dry place away from heat and moisture.
Refrigerate prepared vials between 2–8°C.
Avoid repeated freeze-thaw cycles.
A clear, quick look at what NAD+ is, how it works, and why it is being studied.
NAD+ is connected to cellular energy, recovery, mental clarity, and healthy aging. Every cell needs it to turn food into usable energy and complete everyday repair work.
NAD+ is an essential redox coenzyme and substrate for enzymes involved in energy metabolism, DNA repair, sirtuin signalling and other cellular processes. That central biology explains its broad research interest, but “energy,” “clarity” and “healthy aging” are not interchangeable clinical endpoints. [1–2]
Think of NAD+ as a helper that lets the cell’s engine run. Without enough of it, converting fuel into energy and keeping up with repairs becomes harder.
NAD+ cycles between oxidized and reduced forms during metabolic reactions and is also consumed by enzymes such as sirtuins, PARPs and CD38. It is therefore both a metabolic cofactor and a signalling substrate. [1]
NAD+ takes part in the reactions that turn nutrients into cellular fuel. The interest is not a caffeine-like jolt; it is helping the machinery that produces energy do its job.
NAD+/NADH redox cycling is fundamental to glycolysis, the TCA cycle and mitochondrial oxidative metabolism. That biochemical role is well established; whether raising NAD+ produces a noticeable subjective energy effect depends on intervention, tissue and population. [1–2]
The brain uses a lot of energy, so cellular fuel and mental performance are closely connected. That is why people often discuss NAD+ around focus, clarity, and feeling less mentally drained.
The nervous system depends heavily on energy metabolism, but “mental clarity” is not established simply from NAD+ biochemistry. Human trials of NAD+-raising strategies have produced mixed, endpoint-specific results. [2]
NAD+ levels tend to decline with age while repair demands continue. Supporting the systems tied to energy and cellular maintenance is what gives it such a strong longevity reputation.
NAD+ metabolism changes with age in several tissues and interacts with pathways involved in genomic maintenance, mitochondrial function and stress responses. Human evidence that supplementation broadly slows aging remains much less certain than the mechanistic literature. [1–2]
They are two sides of the same process. Cells need energy to repair, and effective repair helps tissues keep functioning when life, training, or age puts them under stress.
Both themes trace back to cellular metabolism and repair, but they should be separated experimentally. NAD+ participates in energy transfer and is also consumed in DNA-repair/signalling reactions. [1]
No. A stimulant temporarily makes you feel more switched on. NAD+ sits inside the cell’s actual energy and repair processes, so its appeal is deeper than a quick buzz.
No. NAD+ is a cellular coenzyme rather than a classical central-nervous-system stimulant. Its biological role is metabolic and enzymatic, not an acute stimulant mechanism. [1]
Both connect to cellular energy. NAD+ is a basic working molecule used throughout energy and repair, while MOTS-C is a mitochondrial signal studied for how cells respond to fuel and stress.
NAD+ is a ubiquitous small-molecule coenzyme used throughout cellular metabolism; MOTS-c is a mitochondrially encoded signalling peptide. They intersect with metabolic biology but are chemically and mechanistically distinct. [1]
This product is offered for laboratory research only. It is not for human consumption and is not represented as a medicine, treatment, supplement or substitute for an approved product.
Confirm the selected vial and BAC-water amount, enter the target amount, then follow the preparation and storage steps.
The selected strength automatically opens with the easy starting rule of 1 mg = 10 units.
NAD+ · 500 mg selected
Easy rule: 1 mg = 10 units · Every 10 units = 1 mg
This calculator converts the values entered. It does not choose an amount.
This 500 mg vial opens with 50 mL of BAC water, creating the easy starting rule of 1 mg = 10 units.
If the water amount is changed above, use the updated easy rule shown by the calculator.
Do not shake the vialSlowly add the water down the inside wall of the vial, then gently swirl until fully dissolved.
Prepared vialsRefrigerate at 2–8°C
Unprepared vialsKeep cool and dry, away from heat, moisture, and direct sunlight
Every order is prepared and packed in Canada with care, accuracy, and attention to detail. In-stock orders are checked and packed within 24 hours, then shipped with Canada Post. Tracking is sent after the parcel’s first carrier scan.
2 customer reviews
Reviews are checked before publication. Your email is never displayed.
Nice site and helpful chat bot. I’ll be back again.
I can’t believe it but I’ve lost 30lb. It’s been 3 months and felt compelled to write a review. I know it’s not Puffin I have to thank but their site came up in google and brought me here. Thank youuuuuu! <3
Products in the same research area, each with its own pathway, evidence level and selectable strengths.
Puffin Pick
Only logged in customers who have purchased this product may leave a review.
Hi! I’m Ask Puffin. I can explain peptides in plain language and help with products, prices, stock, shipping, and site questions. What can I help with?
Reviews
There are no reviews yet.