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Longevity Research

EPITHALON

Turn the focus toward longevity. Epithalon is a research peptide studied for its potential role in cellular renewal, telomere activity, and the biology of aging—making it a standout for those exploring longevity, regeneration, and long-term cellular health.

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EPITHALON is supplied as 50 mg of lyophilized powder in a sealed glass vial for laboratory research. Confirm the selected vial and batch details before preparation.

Selected strength50 mg
Purity99.87%
TestingHPLC-UV
BatchPP-LOT-012
+ Show Scientific Details− Hide Scientific Details
Primary identityEpitalon
AliasesEpithalon · Epithalone · AEDG
CAS number307297-39-8
Compound classSynthetic tetrapeptide
Peptide length4 amino acids
SequenceAEDG
Molecular formulaC14H22N4O9
Molecular weight390.35 g/mol
Research themesCellular aging · Telomere/telomerase research · Pineal/circadian research
Scientific profile

Epitalon (often sold as Epithalon) is the tetrapeptide Ala-Glu-Asp-Gly (AEDG), studied in cellular-aging and pineal-related research.

Product guide

EPITHALON Explained

A clear, quick look at what EPITHALON is, how it works, and why it is being studied.

What is Epithalon supposed to help with?

Epithalon is best known for longevity, cellular aging, telomeres, sleep, and the body clock. Its appeal is supporting the systems that help cells keep their rhythm and maintain themselves over time.

Research Context

Epithalon is a synthetic tetrapeptide associated with older experimental literature on pineal biology, circadian regulation and cellular aging. The evidence base is much smaller and less independently replicated than modern drug-development programs. [1]

What are telomeres in plain English?

Telomeres are protective caps on the ends of chromosomes, like the plastic tips that stop shoelaces from fraying. They tend to shorten as cells divide and age.

Research Context

Telomeres are repetitive DNA-protein structures at chromosome ends that protect genomic integrity. They generally shorten with repeated cell division, although telomere biology is more complex than a simple clock for whole-body aging. [1]

Why is Epithalon called an anti-aging peptide?

Its early research connects it with telomerase, the enzyme involved in maintaining telomeres. That link put Epithalon at the centre of longevity discussions, although it is not a proven way to reverse aging.

Research Context

A frequently cited cell study reported telomerase activation and telomere elongation in cultured human somatic cells after Epithalon exposure. A cell-culture result is not evidence that Epithalon reverses aging or extends human lifespan. [1]

Can Epithalon make you look younger?

That would be too strong a promise. Its story is about cellular maintenance and aging biology, not an overnight cosmetic transformation.

Research Context

There is no robust modern clinical evidence establishing a cosmetic rejuvenation effect. Cellular aging mechanisms should not be translated directly into guaranteed visible changes. [1]

Why do people discuss Epithalon for sleep?

Sleep depends heavily on circadian rhythm—the body’s internal clock. Epithalon research has explored pineal and melatonin-related biology, which is why sleep appears beside longevity.

Research Context

Epithalon has historical research connections to pineal and circadian biology, but the human sleep evidence is limited compared with established sleep interventions. Mechanistic interest should be kept separate from proven clinical benefit. [1]

What could a healthier body clock feel like?

Think feeling sleepy at a sensible time, waking more naturally, and having energy arrive when the day begins instead of at the wrong hours.

Research Context

Circadian function affects sleep timing, hormone rhythms and metabolism, but a subjective “better body clock” requires validated sleep/circadian outcomes rather than inference from peptide mechanism. [1]

Is Epithalon mainly for sleep or longevity?

Longevity is the bigger theme, but sleep rhythm is part of how the body maintains and repairs itself. The two interests fit together rather than competing.

Research Context

Longevity is the larger research narrative, while circadian/pineal biology is one proposed pathway. Neither theme has a large contemporary randomized human evidence base. [1]

How is Epithalon different from NAD+?

Epithalon is associated with telomeres and circadian biology. NAD+ is involved directly in cellular energy and repair. They approach healthy aging from different directions.

Research Context

Epithalon is a tetrapeptide associated with telomerase/pineal research; NAD+ is a ubiquitous cellular coenzyme central to redox metabolism and enzyme signalling. Their proposed longevity narratives arise from different biology. [1]

Read the full Epithalon evidence guideStudy design, primary sources, limitations, and unanswered questions.Open guide
Research-use statement

This product is offered for laboratory research only. It is not for human consumption and is not represented as a medicine, treatment, supplement or substitute for an approved product.

Preparation guide

Calculate. Prepare. Store.

Confirm the selected vial and BAC-water amount, enter the target amount, then follow the preparation and storage steps.

Step 1: Calculate

The selected strength automatically opens with the easy starting rule of 1 mg = 10 units.

EPITHALON · 50 mg selected

Vial Strength
50mg

Easy rule: 1 mg = 10 units · Every 10 units = 1 mg

Calculated result
U-100 syringe20 units2 mg at the current water amount

This calculator converts the values entered. It does not choose an amount.

Step 2: Prepare

This 50 mg vial opens with 5 mL of BAC water, creating the easy starting rule of 1 mg = 10 units.

If the water amount is changed above, use the updated easy rule shown by the calculator.

Do not shake the vialSlowly add the water down the inside wall of the vial, then gently swirl until fully dissolved.

Step 3: Store

Prepared vialsRefrigerate at 2–8°C

Unprepared vialsKeep cool and dry, away from heat, moisture, and direct sunlight

Shipping & delivery

Picked And Shipped Within 24 Hours.

Every order is prepared and packed in Canada with care, accuracy, and attention to detail. In-stock orders are checked and packed within 24 hours, then shipped with Canada Post. Tracking is sent after the parcel’s first carrier scan.

Bilingual Shipped by Canada Post logo with English to the left and French to the right

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Product documentation

Batch Details

Uploaded documents50 mg
PDF · 50 mgPP-EPITHALON-50-MG-R012.pdfPublished for EPITHALON 50 mg
View document
ProductEPITHALON
Strength50 mg
Catalogue codePP-EPITHALON-50-MG
PresentationLyophilized powder in a sealed glass vial
StorageSee vial label and lot-specific documentation
Intended useLaboratory research only · not for human consumption

Only uploaded documents published for the selected vial strength are shown here.

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