Full vial shown · package appearance may vary by batch24/7 Customer Support
Lab tested for purity & quality
Ships from Canada within 24 hours
At Puffin Peptides, we work with an established Canadian manufacturer and handle packaging and fulfilment here in Canada. Keeping the process close to home gives us better visibility into quality, consistency, packaging, and the batches moving through our catalogue.
That means clearer product information, accessible batch documentation, responsive local support, and a more dependable ordering experience from checkout to delivery.
Our focus is simple: well-made research products, straightforward information, and reliable Canadian service.
Bring out a deeper, more sun-kissed look. Melanotan II is a research peptide studied for its ability to stimulate melanin production, support darker pigmentation, and enhance the body’s natural tanning response—making it especially appealing for those exploring pigmentation, tanning, and melanocortin-related research.
MELANOTAN II is supplied as 10 mg of lyophilized powder in a sealed glass vial for laboratory research. Confirm the selected vial and batch details before preparation.
Melanotan II is a synthetic cyclic melanocortin analogue designed to activate melanocortin-receptor signalling and has been studied in human pigmentation research.
Acetate salt records have different molecular weights and CAS values; acetate-specific identifiers are not substituted because the supplied form has not been confirmed.
This 10 mg vial opens with 1 mL BAC water.
The default easy rule is 1 mg = 10 units on a U-100 syringe. Changing the water amount updates that relationship automatically.
Want to measure an mg amount?Open the reconstitution calculatorStore unprepared vials in a cool, dry place away from heat and moisture.
Refrigerate prepared vials between 2–8°C.
Avoid repeated freeze-thaw cycles.
A clear, quick look at what MELANOTAN II is, how it works, and why it is being studied.
Melanotan II is best known for increasing skin pigmentation. It signals pigment-producing cells to make more melanin—the natural colour that makes skin appear darker.
Melanotan II is a synthetic cyclic melanocortin analogue that activates melanocortin receptors. A small phase-I study documented increased pigmentation in human volunteers, while also observing systemic effects such as nausea, fatigue and spontaneous erections. [1]
Instead of colouring the surface like a lotion, it acts on the biological signal behind melanin production. Think encouraging the skin’s pigment factory rather than painting colour on top.
Melanocortin signalling can stimulate melanogenesis in pigment-producing cells. The mechanism changes endogenous melanin production rather than applying pigment to the skin surface. [1]
It may increase pigmentation, but UV exposure still affects how tanning develops. More melanin does not make excessive sun exposure safe or remove the need for sun protection.
Human pilot data showed increased pigmentation after Melanotan II exposure, but UV exposure also influences melanogenesis. Increased pigmentation should not be interpreted as protection from UV injury. [1]
Self-tanner temporarily colours the outermost skin cells. Melanotan II acts on melanocortin receptors involved in the body’s own pigment production.
Cosmetic self-tanners typically colour the stratum corneum through surface chemistry; Melanotan II acts pharmacologically at melanocortin receptors and can have systemic effects beyond pigmentation. [1]
No. Natural skin tone, pigment response, freckles, moles, and UV exposure all affect appearance. Biology does not produce one identical shade for every person.
Pigmentation depends on baseline phenotype, melanocyte biology, UV exposure and individual response. A melanocortin agonist cannot be expected to produce one uniform cosmetic result. [1]
Those areas already contain concentrated pigment-producing cells. When melanin signaling rises, existing pigmented spots may respond along with the surrounding skin.
Melanocortin signalling affects melanocytes broadly, including cells within existing pigmented lesions. Changes in freckles or nevi are one reason pigmentation effects should not be treated as equivalent to a topical cosmetic. [1]
Yes. The melanocortin system also connects to appetite and sexual function. Those wider effects are why it should not be thought of as an ordinary cosmetic tanning lotion.
Yes. Melanocortin receptors participate in multiple physiological systems. The early human study reported effects including nausea, fatigue and spontaneous erections, demonstrating that Melanotan II is not a skin-only signal. [1]
The attraction is a tan produced through the body’s own pigment pathway rather than surface colour. That unique mechanism is also why understanding its broader effects matters.
Interest comes from its ability to stimulate endogenous pigmentation through melanocortin biology. The same receptor activity that makes the mechanism distinctive also means its systemic effects and evidence limitations matter. [1]
This product is offered for laboratory research only. It is not for human consumption and is not represented as a medicine, treatment, supplement or substitute for an approved product.
Confirm the selected vial and BAC-water amount, enter the target amount, then follow the preparation and storage steps.
The selected strength automatically opens with the easy starting rule of 1 mg = 10 units.
MELANOTAN II · 10 mg selected
Easy rule: 1 mg = 10 units · Every 10 units = 1 mg
This calculator converts the values entered. It does not choose an amount.
This 10 mg vial opens with 1 mL of BAC water, creating the easy starting rule of 1 mg = 10 units.
If the water amount is changed above, use the updated easy rule shown by the calculator.
Do not shake the vialSlowly add the water down the inside wall of the vial, then gently swirl until fully dissolved.
Prepared vialsRefrigerate at 2–8°C
Unprepared vialsKeep cool and dry, away from heat, moisture, and direct sunlight
Every order is prepared and packed in Canada with care, accuracy, and attention to detail. In-stock orders are checked and packed within 24 hours, then shipped with Canada Post. Tracking is sent after the parcel’s first carrier scan.
2 customer reviews
Reviews are checked before publication. Your email is never displayed.
Nice site and helpful chat bot. I’ll be back again.
I can’t believe it but I’ve lost 30lb. It’s been 3 months and felt compelled to write a review. I know it’s not Puffin I have to thank but their site came up in google and brought me here. Thank youuuuuu! <3
Products in the same research area, each with its own pathway, evidence level and selectable strengths.
Puffin Pick
Only logged in customers who have purchased this product may leave a review.
Hi! I’m Ask Puffin. I can explain peptides in plain language and help with products, prices, stock, shipping, and site questions. What can I help with?
Reviews
There are no reviews yet.