Skip to content
Every Peptide Explained & Sourced
Performance Research

TESAMORELIN

5.0ReviewsRead more

Target stubborn visceral fat with precision. Tesamorelin is a growth-hormone-releasing peptide designed to stimulate the body’s natural hormone production, supporting fat metabolism, lean tissue, recovery, and improved body composition—especially around the midsection.

Batch details included Manufactured in Canada
$126 CADCAD · shipping and taxes shown at checkout

TESAMORELIN is supplied as 5 mg of lyophilized powder in a sealed glass vial for laboratory research. Confirm the selected vial and batch details before preparation.

Selected strength5 mg
Purity99.28%
TestingHPLC-UV
BatchPP-LOT-039
+ Show Scientific Details− Hide Scientific Details
Research designationTH9507
CAS number218949-48-5
Compound classSynthetic GHRH analogue
Peptide length44 amino acids
SequenceYADAIFTNSYRKVLGQLSARKLLQDIMSRQQGESNQERGARARL
Molecular formulaC221H366N72O67S
Molecular weight5136 g/mol
Primary targetGrowth-hormone-releasing hormone receptor (GHRHR)
Scientific profile

Tesamorelin is a stabilized synthetic analogue of growth-hormone-releasing hormone designed to activate GHRH signalling and stimulate endogenous growth-hormone secretion.

Product guide

TESAMORELIN Explained

A clear, quick look at what TESAMORELIN is, how it works, and why it is being studied.

What is Tesamorelin supposed to help with?

Tesamorelin is best known for visceral abdominal fat, body composition, and growth-hormone release. It attracts people focused on the deeper belly fat that sits around internal organs.

Research Context

Tesamorelin is a growth-hormone-releasing hormone analogue with human randomized-trial evidence for reducing visceral adipose tissue in people with HIV-associated abdominal fat accumulation. Evidence from that defined population should not automatically be generalized to all forms of obesity or body composition. [1–2]

What is visceral fat in plain English?

It is the fat packed deeper inside the abdomen around the organs, not just the softer layer you can pinch. That deeper location is why it matters for more than appearance.

Research Context

Visceral adipose tissue is fat stored within the abdominal cavity around internal organs, distinct from subcutaneous fat under the skin. It is measured more accurately with imaging than by appearance alone. [1–2]

Why is Tesamorelin linked to belly fat?

Its strongest clinical connection is reducing excess visceral abdominal fat in a specific approved population. That is why it stands apart from general ‘lose weight everywhere’ products.

Research Context

Randomized trials in HIV-associated abdominal adiposity found significant reductions in visceral adipose tissue, which is why tesamorelin has a more specific visceral-fat evidence base than general “fat-loss” compounds. [1–2]

Does Tesamorelin simply make you eat less?

No. Appetite control is not its main story. It encourages growth-hormone release, connecting it more directly to fat metabolism and body composition than hunger.

Research Context

Tesamorelin acts through GHRH receptors to stimulate endogenous growth-hormone secretion and increase IGF-1; appetite suppression is not its primary established mechanism. [1–2]

Will it target the soft fat I can pinch?

Its reputation is specifically about deeper visceral fat, so it should not be described as a guaranteed spot-treatment for every kind of belly fat.

Research Context

The strongest clinical evidence concerns visceral rather than subcutaneous abdominal fat. It should not be described as a guaranteed spot-reduction treatment for superficial fat. [1–2]

How is Tesamorelin different from Semaglutide?

Semaglutide mainly helps control hunger and fullness. Tesamorelin works through growth-hormone signaling and is especially associated with deeper abdominal fat.

Research Context

Tesamorelin stimulates the GH/IGF-1 axis and has specific visceral-fat evidence in an HIV-associated population; semaglutide is a GLP-1 receptor agonist with a much broader obesity/diabetes clinical program centred on appetite and metabolic regulation. [1–2]

How is Tesamorelin different from Ipamorelin?

Both encourage growth-hormone release, but Tesamorelin has a much more specific connection to visceral abdominal fat. Ipamorelin is discussed more broadly around recovery, sleep, and body composition.

Research Context

Both can stimulate endogenous GH release, but tesamorelin is a GHRH analogue with substantial human clinical data in a defined visceral-adiposity indication; ipamorelin is a ghrelin-receptor/GH-secretagogue agonist with a much smaller clinical evidence base. [1–2]

Why are people excited about Tesamorelin?

Because stubborn belly fat is frustrating, and visceral fat is difficult to understand from the mirror alone. Tesamorelin gives that specific problem a more focused research story.

Research Context

The interest is supported by actual randomized human data on visceral adipose tissue, not just mechanism. The key limitation is population specificity: the strongest trials were not general weight-loss studies in otherwise healthy adults. [1–2]

Read the full Tesamorelin evidence guideStudy design, primary sources, limitations, and unanswered questions.Open guide
Research-use statement

This product is offered for laboratory research only. It is not for human consumption and is not represented as a medicine, treatment, supplement or substitute for an approved product.

Preparation guide

Calculate. Prepare. Store.

Confirm the selected vial and BAC-water amount, enter the target amount, then follow the preparation and storage steps.

Step 1: Calculate

The selected strength automatically opens with the easy starting rule of 1 mg = 10 units.

TESAMORELIN · 5 mg selected

Vial Strength
5mg

Easy rule: 1 mg = 10 units · Every 10 units = 1 mg

Calculated result
U-100 syringe20 units2 mg at the current water amount

This calculator converts the values entered. It does not choose an amount.

Step 2: Prepare

This 5 mg vial opens with 0.5 mL of BAC water, creating the easy starting rule of 1 mg = 10 units.

If the water amount is changed above, use the updated easy rule shown by the calculator.

Do not shake the vialSlowly add the water down the inside wall of the vial, then gently swirl until fully dissolved.

Step 3: Store

Prepared vialsRefrigerate at 2–8°C

Unprepared vialsKeep cool and dry, away from heat, moisture, and direct sunlight

Shipping & delivery

Picked And Shipped Within 24 Hours.

Every order is prepared and packed in Canada with care, accuracy, and attention to detail. In-stock orders are checked and packed within 24 hours, then shipped with Canada Post. Tracking is sent after the parcel’s first carrier scan.

Bilingual Shipped by Canada Post logo with English to the left and French to the right

Customer Reviews

5.0★★★★★

2 customer reviews

Share your experience

Reviews are checked before publication. Your email is never displayed.

2 reviewsShowing 2
Lacey HughesVerified buyer
★★★★★
Puffin Peptides

Nice site and helpful chat bot. I’ll be back again.

Kimmy SonnVerified buyer
★★★★★
Puffin Peptides

I can’t believe it but I’ve lost 30lb. It’s been 3 months and felt compelled to write a review. I know it’s not Puffin I have to thank but their site came up in google and brought me here. Thank youuuuuu! <3

Reviews

There are no reviews yet.

Only logged in customers who have purchased this product may leave a review.

Product documentation

Batch Details

Uploaded documents5 mg
PDF · 5 mgPP-TESAMORELIN-5-MG-R039.pdfPublished for TESAMORELIN 5 mg
View document
ProductTESAMORELIN
Strength5 mg
Catalogue codePP-TESAMORELIN-5-MG
PresentationLyophilized powder in a sealed glass vial
StorageSee vial label and lot-specific documentation
Intended useLaboratory research only · not for human consumption

Only uploaded documents published for the selected vial strength are shown here.

Search the catalogue

What Are You Looking For?